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Thromboxane has been implicated as a mediator of pulmonary hypertension and pulmonary edema in acute respiratory failure.
Nitric oxide (NO) synthesized by inducible nitric oxide synthase (iNOS) has been implicated as a mediator of inflammation.
Objectives: Apoptosis caused by acute ischemia and subsequent ventricular remodeling is implicated as a mediator of heart failure.
Interleukin (IL) 15 is an inflammatory cytokine that plays an essential role in the activation, proliferation, and maintenance of specific natural killer cell and T-cell populations, and has been implicated as a mediator of inflammatory diseases.
Although substance P (SP) has been implicated as a mediator of neurogenic inflammation in the small intestine, little information is available regarding the role of SP in the pathogenesis of chronic ulcerative colitis.
HuR was implicated as a mediator of MK2-induced uPAR mRNA stabilization, suggesting a link between the p38 activation pathway, HuR translocation and inflammatory transcript stabilization [4].
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Originally implicated as a later mediator of sepsis [ 6], recent work [ 7, 8] has shown that HMGB1 is an early mediator of injury and inflammation in liver IRI, and demonstrates a rapid increase in plasma levels following tissue reperfusion.
Glucagon has also been implicated as a potential mediator of intestinal adaptation.
Glucagon has been implicated as a potential mediator of intestinal adaptation.
Cardiac autonomic abnormalities have been implicated as a potential mediator of cardiovascular events and sudden death in depression.
The up-regulation of the receptor for advanced glycation end products (RAGE) has been implicated as a major mediator in the development and progression of diabetic nephropathy and hepatic fibrogenesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com