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While previous analyses have implicated a small number of uPEPs in cis-acting post-transcription regulation, we believe that the presence of hundreds of uORFs, which are strongly conserved at the peptide level, suggests other biological roles for uPEPs.
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In total, these results implicate a small number of genes, particularly a cluster related to dopamine D1 signalling in the PFC, as being related to and potentially as being mediators of general cognitive abilities (c.f., general intelligence).
These analyses implicate a small number of highly conserved and apparently essential amino acids within the domain.
Earlier research has begun to implicate a small subset of appendage patterning genes in horn development (Distal-less, dachshund, extradenticle, homothorax, [ 11, 13, 15]).
However, their gas-phase results did implicate a small exothermicity of a homolytic pathway to form an iron(IV oxo species, but this pathway would require an additional electron transfer, which is not possible in our system.
Going forward, sRNA-target pairs will be combined with gene expression data to search for defense-related genes that are unexpectedly downregulated in response to infection, possibly implicating a small RNA-based effector.> This research contributes an inventory of small RNAs from one member of an important group of plant pathogens: the rust fungi.
The responses have implicated alcohol – a small daily glass of wine increases breast cancer risk by 6%.
Although transgenic mutant SOD1 animals, which provide the most widely studied models of the disease, display many of these features, therapeutic efficacy in these animals has been poorly predictive of human efficacy, and it is not clear the degree to which studies in these models overexpressing a gene implicated in a small subset of human cases will prove applicable to human disease.
This implicates a rather small interaction site between the receptor and the G protein.
Anaesthesia by severe hypothermia induces almost no lethality, the injection implicates only a small incision of the skin and skull, positioning of the injection needle is controlled by a stereotaxtic device and the volume of the injected liquid is well defined via a microsyringe.
The stepwise nature of the process resulting in T1D, is illustrated in our study by the difficulty to sort out a clear mechanism describing a possible scenario for disease initiation and implicating, preferably, a small number of molecules.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com