The deletion analysis implicated a sequence upstream of the sigma 54 promoter, as well as a region downstream of the transcription start site, in the functioning of the promoter.
In this study, time-dependent BOLD activity changes in the region of interest implicated a sequence of cortical gray matter blood flow changes beginning with hyperemia, followed by hypoperfusion with attenuated response to visual activation and subsequent return of resting blood flow to baseline with recovery of stimulus driven activation [ 89].
Crystal structures of the free and CMP-Kdo-bound forms of KdtA from Aquifex aeolicus reveal details of the CMP-binding site and implicate a unique sequence motif in Kdo binding.
Comparison of pretreatment and posttreatment sequences implicated an amino acid in CDR2 as being involved in the idiotypic determinant.
In addition, in contrast to HMRs in CGIs, nucleosomes at the boundaries of non-CGI HMRs are predicted by a model of intrinsic nucleosome occupancy [ 33], suggesting that nucleosomes are localized at their preferred sites, implicating a role for DNA sequence in demarcating these putative regulatory regions genome-wide.
P. falciparum apPOL, the first structural representative of a plastidic A-family polymerase, diverges from typical A-family members in two of three previously identified signature motifs and in a region not implicated by sequence.
This is to be expected because the presence of a given TCR sequence does necessarily implicate a particular T cell clone in disease pathogenesis.
Subsequently, we experimentally validated a subset of computationally inferred patterns of overlapping AS patterns, by RT-PCR and direct sequencing, analyzed implicated sequence and transcript features, and compared A5Es with constitutive and pseudo-exons, as well as A3Es, in H. sapiens and M. musculus.
A recent study implicates an association between rare sequence variants in NR2F2 and AVSD in nonsyndromic individuals (Al Turki et al. 2014).
As such, it is important to understand the mobilization of such islands, which we note, cannot be achieved through genomic analyses alone as there is no sequence-based signature that implicates a role for ICP1 in PLE mobilization.
Cortical regions implicated in the control of voluntary movement include the supplementary motor complex, which comprises supplementary and pre-supplementary motor areas (SMA; preSMA) and has also been implicated in sequence learning (Nachev et al. 2008), and primary motor cortex (M1) that has been closely associated with motor skill acquisition (Li et al. 2001; Muellbacher et al. 2002).
