Sentence examples for implicate constraints from inspiring English sources

Thus, although the CGCGCg integration site is a palindromic sequence, we believe that selection of the second site might not necessarily implicate the presence of a palindrome but rather implicate constraints brought by the DNA structure or conformation.

This implicates functional constraints on the structure of operons containing mtrH homologs in nonmethanogens.

These results implicate health systems constraints in child mortality, quantify the contribution of specific domains of health services, and suggest priority areas for improvement to accelerate reductions in child mortality.

Although they are not part of the PTC per se, mutations at residues close to the PTC in L3 and L16 ribosomal proteins could still be implicated in releasing constraints associated with the acquisition of the unfavorable G2576T 23S rRNA mutation by altering the conformation and/or stability of the PTC through changes in second- and third-shell interactions.

Our present findings in agnathans reinforce this trend, and further suggest that this signaling pathway is highly versatile and may be recruited to very divergent processes, implicating also that the constraints on its regulation of expression must be surprisingly weak.

While we have not excluded the possibility that reactivation of positive regulators of cyclins and cyclin-dependent kinases might contribute to cell cycle re-entry in adult myocytes [29], the present study implicates relief of constraint from the 14-3-3/p21/p53 patheay in thenhanceded proliferative potential of dedifferentiating myocytes.

Regions of high evolutionary constraints are usually implicated in maintaining structural or functional integrity of the protein.

Ohno [ 1] theorized that newly duplicated genes were freed from the constraints of natural selection, implicating a dominant role of genetic drift in their early evolutionary dynamics.

Recognizing that many metabolites are involved in multiple reactions, a "metabolite-centric" approach can potentially find individual metabolite targets implicating some combination of reaction flux constraints.

These results implicate the solvent capacity as an important physiological constraint acting on E. coli cells operating at high metabolic rates and for the activation of a metabolic switch when they are shifted from low to high growth rates.

From a more general perspective the results reported in this study further implicate the limited solvent capacity as an important constraint acting on the metabolism of cells operating at high metabolic rates.