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Current results implicate a model in which calcium binds to ALG-2 when intracellular calcium levels reach a certain threshold value (la Cour et al. 2007).
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24 This breakthrough could implicate a novel model for future treatments.
Together, these results provide insight into the molecular mechanism of Aureo function and implicate a new model of light-dependent gene regulation by Aureos in stramenopiles.
Other research has, however, implicated a causal model whereby problems with alcohol have led to depression, or alternatively a self-medication model in which depression leads to increased the risk of AUD [ 34].
Either way you slice it, there is a lot of water in the transition zone: "Both models implicate a transition zone that is at least locally water-rich," he wrote.
In addition to its role in left-right patterning, compelling evidence from recent studies using mouse models implicate a complex and critical role for the cilium in CHD pathogenesis in a much broader context (Friedland-Little et al. 2011; Li et al. 2015).
Potten, C.S. & Allen, T.D. A model implicating the Langerhans cell in keratinocyte proliferation control.
However, additional models that implicate a breakdown in negative selection as the driving force behind the development of autoimmune disease are lacking (von Boehmer and Melchers, 2010).
With the limitations discussed above, a number of studies in disease models clearly implicate a pivotal role for chaperones and protein misfolding in the pathogenesis of PD and other synucleinopathies.
Our current findings add to earlier gene expression studies in blood that have reported a number of potential peripheral biomarkers for bipolar disorder [50], [51], and earlier gene expression findings in brain indicating that clock genes are implicated in a model of bipolar disorder, the first report being [52], followed by [53] for CRY2.
On the other hand, inadequate angiogenesis has been implicated in a model of interstitial renal fibrosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com