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FBAT implements the method of Laird et al. [48] and performs family-based association tests.
EIGENSTRAT implements the method of Price et al. [6], and performs univariate association tests (continuous or binary) for unrelated samples.
Randomise implements the method of permutation testing based on randomisation to correct for the multiple comparisons involved in testing across all image voxels to adequately protect against false-positive detections as described in detail by Nichols and Holmes [26].
oncor implements the method of Rannala and Mountain (1997) to estimate baseline allele frequency distributions.
GCTA (Genome-wide Complex Trait Analysis) tool implements the method of estimating variance explained by all SNPs and extends the method to partition the genetic variance onto each of the chromosomes.
For CDS-C and CDS-NC, we calculated K A and K S (the numbers of nonsynonymous and synonymous substitutions per nonsynonymous and synonymous site, respectively) using the kaks function from the seqinr package (Charif and Lobry, 2007) in R (http://www.r-project.org/), which implements the method of Li (1993).
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In fact, the module is a constructor that implements the methods of querying data sampling with different requirements and criteria.
The haplo.stats program implements the methods of Schaid et al. [ 50] and was used for these analyses.
To do this we need to recruit 400 patients (calculation using the pwr package in R, which implements the methods of Cohen (1988) for a linear model) [ 17].
In the case of the university's patent, he said, "there was no way to implement the method of treatment".
To further examine ACOCOA's robustness, we have implemented the method of watermark removal attack [33] for comparison.
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