One of the interesting things is that the basic biological network of genes and proteins that implement the cell cycle is the same in all eukaryotes.
It is probable that this response time is related in part to the recovery of N-receptor function, the time required to implement the cell response and to a particularly low level of cell responsiveness to the N-pathway during the last hour of life.
EM implemented the cell cycle model section of the database and the simulation pipeline.
For wounding, the SSM cell culture substratum was scratched with a sharp implement: the cells lining the site denuded by the scratch suffer disruption injuries [15].
The cell cycle terms in the second row of Equation (4) implement the continuous cell cycle model of León et al. [50] without G0 phase arrest.
We developed a MODCELL (modular cell) framework based on metabolic pathway analysis to implement the modular cell design principle.
As mentioned in Section 3.3, a small cell in the sleep state is required to transit to the on state in a very short time (e.g., [6] considers an activation time of 40 ms), in order to guarantee the dynamicity required to implement the small cell energy savings schemes introduced in this paper.
We implemented the stem cell regulatory network as a system of ordinary differential equations (ODEs) using standard mass action kinetics for molecular reactions.
These findings suggest that additional research will be required before implementing the genetically engineered Vero cell lines in the manufacturing process for polio- and rotavirus vaccines to be able to supply vaccines at reduced prices.
The spatiotemporal organisation of the molecular components enabling and implementing the specification of these cell types are well known (Pfister et al., 2007) and the sequence of events can be mimicked in culture (Kubo et al., 2004; Gadue et al., 2006), albeit in a spatially disorganised manner and often with low yields of cells of a particular fate.
