In case hypoglycemia occurs, in our burn centre we implemented infusing 50 cm3 dextrose in water (50%) intravenously and readjusting the insulin infusion protocol (see Figure 1).
Implementing an infusion model is relatively simple.
These savings must be balanced against the higher economic costs of implementing the closed infusion container system.
Given frequent IRRs, demonstrated techniques to reduce the IRRs were implemented, including increased infusion volume, increased infusion time, and premedication with IV glucocorticoids.
We present the implementation of a new thin silicon microneedle for deep brain drug infusion implemented using a fabrication technology called glass cover on silicon technology (GCoS) that embeds microchannels in silicon substrate.
Based on those findings, we initiated a prospective observational study implementing a continuous insulin intravenous infusion protocol as recommended internationally in our patients, both diabetic and nondiabetic, to achieve a blood glucose level (BGL) between 4 and 8 mmol/l.
Furthermore, SAHZU has required that two licensed health care professionals must perform a "double check" prior to administering intravenous infusions of insulin, by implementing a standardized independent double-check process, since January 2013.
These data provided the rationale for implementing phase I/II clinical trials of adoptive infusion of either selected or ex vivo-activated NK cells, often from an HLA-mismatched donor.
In addition, persons handling or entering an infusion should only do so after implementing appropriate infection control measures and with strict adherence to aseptic technique [ 42].
It is usually the hospital rather than society who serves as the decision maker when it comes to implementing new infection control interventions such as the use of new drug infusion containers.
Following the observation of renal toxicities, hydration using 1000 to 1500 ml of fluid, immediately after NC-6004 infusion, was implemented for the rest of the study.
