The present study was designed to overcome this conceptual framework by implementing a dose-dense anthracycline-containing regimen for patients with cardiac comorbidity through strict patient monitoring.
Finally, our study will also implement a dosing regimen that is consistent with the findings of the previously mentioned pharmacokinetic studies that will likely improve the CINV protection of this therapy.
"Many other countries have successfully started implementing a second dose of measles vaccination in recent years with a sharp drop in measles related mortality".
The cost of implementing a 3-dose PCV-7 vaccination schedule for a birth cohort of nearly 16,000,000 Chinese infants was estimated to be $6.44 billion.
As described in a later section on feedback control strategies, overdosing with substrate can be prevented by implementing an automated dosing strategy based on monitoring the dissolved oxygen concentration.
This is probably why some countries (i.e. Austria and Switzerland) have implemented a booster dose at adolescent age in addition to the vaccine dose in the second year of life (Table 1).
An order for 60,000 doses intended to implement a 3-dose strategy covering 20,000 people may vary relatively little in price compared with an order also for 60,000 doses intended to implement a 2-dose strategy covering 30,000 people.
The United Kingdom and Spain implemented a 3-dose primary series at 2, 3 and 4 months and 2, 4 and 6 months of age, respectively.
However, compared with PA, TO and its prodrug Race induced less potent increases of tumor uptake, highlighting the significance of inhibitor type, administration route, and dose for implementing a first proof-of-principle study in human.
We defined guidelines as statements developed systematically to assist practitioner's decision-making in cancer care (Woolf et al, 1999), and defined protocols as evidence-based statements assisting practitioners in implementing treatment choices (specific information on implementing a particular chemotherapy protocol, e.g., dosing, scheduling, and monitoring).
An amendment to the protocol was implemented to test a dose level of 12.5 μg/kg.
