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The implemented workflow is microarray platform independent and is presented as a web-based service.
Figure 1 shows the implemented workflow.
Instead, it is a telemedicine network, with a distributed archive, with an implemented workflow and quality improvement cycle.
All data, including the exact input data used, intermediate data, third party data, output data, and their provenance, were captured and preserved within our implemented workflow.
The experimental process using Isotopo consists of three major steps: data preparation, analysis and visualization as shown in Figure 1, following the implemented workflow as shown in Figure 2a.
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Currently implemented workflows include those for adapter trimming, read mapping, peak calling, motif discovery, transcript assembly, variant calling and chromatin conformation analysis.
The implemented workflows currently use BLAST+ (Camacho et al., 2009) version 2.2.28+ using any of the blastn, megablast or tblastx algorithms and nucleotide LAST (Frith et al., 2010) version 320.
This article draws on the authors' own experiences designing, planning and implementing workflow for two digital imaging projects, including using an SGML/XML metadata standard to provide access to digitized resources in all formats.
To demonstrate grid architecture, we will encapsulate death records using the OGSA Data Architecture and implement workflow to access grid-enabled text processing and analytic tools.
Although there are a plethora of orchestration frameworks to implement workflows, most of them are unsuitable for executing (enacting) data-centric workflows since they are based on a centralized orchestration engine which can be a bottleneck when handling large data volumes.
Based on these guidelines, users should be able to implement workflows using irreversible image compression.
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