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Although it is generally accepted that randomised controlled trials provide the highest level of evidence, a non randomised controlled design was implemented in this study as it mirrors real life clinical practice and is the most cost neutral design for the limited resources available [ 24].
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The different analytical approaches implemented in this study can be seen as complementary and together yielded robustness that would not have been possible with any one method alone.
However, it should be noted that BLUP|GA as implemented in this study is a general approach which encloses GBLUP as a special case (with either weight or top% being 0), and thus will "automatically" find the best model which might be close to GBLUP in many cases when calibrated.
Since no inductions of classifiers are to be implemented in this study, whole datasets are used as training sets during feature selection.
The results do not however, provide an imperative to introduce multi-disciplinary care teams, adherence counseling, or personalized nursing services as implemented in this study.
No effect of IST was observed on educational achievement in the older class, but an apparent negative effect was seen on spelling scores in the younger class at 9 and 24 months and on arithmetic scores at 24 months.In this setting in Kenya, IST as implemented in this study is not effective in improving the health or education of school children.
Consequently, the necessary Tykhonov matrix, which can be used in the regularized estimation of the Euler vector, is not available and has to be developed analytically as implemented in this study.
Integration of mouse model and cell line data as implemented in this study provides an innovative strategy that would be applicable to other cancer types for the discovery of circulating biomarkers.
MSMs, as implemented in this study, require a number of assumptions and a rather simple data structure.
Multiple strategies and opportunities for participation, as implemented in this study and recommended in knowledge translation approaches, will likely maximize involvement [ 49].
The Teaching Team model of peer instruction as implemented in this study provided benefits to all team members: students, preceptors (Table 7), TAs, and the instructor.
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