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The method is implemented in the program SCOToolkit.
The structures were solved by molecular replacement, as implemented in the program PHASER23.
Node ages were estimated using a Bayesian molecular clock model implemented in the program BEAST v1.8.051,52.
A haplotype network was generated using the median-joining algorithm89 implemented in the program PopART v.1.726.
All simulations were performed using the GROMOS force field, implemented in the program THOR.
The structure was solved by direct methods as implemented in the program SHELXS-97 [27].
Four different parameterizations of equation 4 are implemented in the program.
Corresponding structural parameters were derived by full-profile Rietveld method implemented in the program package WinCSD [27].
This type of approach is implemented in the program MEGAN4.
Such an approach was implemented in the program BAli-Phy.
This approach has been implemented in the program MSASA (Multiple Sequence Alignment by Simulated Annealing).
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