Site-wise models implemented in Selecton indicated strong purifying selection acting on all investigated genes, with only two genes (fkbp4 and rhob) having sites under significant positive selection.
An electronic reporting system for a network of 22 laboratories was implemented in Kansas City, Missouri, with an independent organization acting as a data clearinghouse between the reporting laboratories and public health departments.
In addition to applying the SL concept to tumour suppressor genes, an analogous strategy has been successfully implemented for dominantly acting oncogenes and specifically for KRAS.
In the original study36, these modules were considered as implemented in different brain areas with lateral intraparietal area (LIP) acting as an accumulator and the superior colliculus, which contains burst neurons that demonstrate perimovement discharges, as the threshold detection mechanism.
By using Site-Models implemented in PAML4, we evaluated the variation of selective pressure acting on Nlrp4 and Nlrp9 duplicates, respectively.
In another study of hip fracture patients, a nurse-led interdisciplinary intervention program for delirium was implemented in the experimental group using a short-acting weak opioid analgesic in combination with acetaminophen, while the control group received usual care.
This procedure has been implemented in the SCOREASSOC program, which also implements a weighted burden test to detect dominantly acting effects.
Selective pressures acting on the V1r receptor genes were assessed using different models as implemented in the PAML software v.3.15 [36].
The objective of this study was to develop a fast-acting, single-dose NiV vaccine that could be implemented in a ring vaccination approach during outbreaks.
We tested for selection acting on the nuclear loci by using the HKA test [ 46], as implemented in DNASP 5.0 [ 47].
The mode and intensity of selection, ω (∼dN/dS, the ratio of non-synonymous to synonymous substitution rates), acting on each locus was estimated using a codon-based substitution model [40] as implemented in PAML's program codeml [41].
