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Such a system has been implemented by fusing avidin and streptavidin with the transmembrane domain of VSV-G [ 4].
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The initial fused volume had 65,535 different levels in the RG space, so a minimum variance quantisation (MVQ) algorithm, which uses Floyd-Steinberg's 'error diffusion dither principle' [ 26] implemented by the MATLAB function 'rgb2ind' [ 25] was used to reduce colour depth to a more manageable number of levels.
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