Sentence examples for implementation surrogates from inspiring English sources

This may be a consequence of the bluntness of these Calman Hine implementation surrogates but developing sharper measures to quantify organisational change is extremely difficult.

If applied in full by regulatory authorities, very few biomarkers in medicine live up to these requirements, which may obstruct implementation of surrogate biomarkers in large-scale clinical trials.

In spite of advantages in sourcing and expansion of these cells, significant barriers still exist to their implementation as reliable surrogates for primary hepatocytes.

Its purpose will be to demonstrate (a) whether population-wide implementation produces interim surrogate outcome measures (e.g. reduction in risk score or short-term incidence) comparable to those tested in trials such as the DPP at equal or lower costs, and (b) to make such studies of population-wide interventions comparable across context populations.

The method uses the number of sensors as a surrogate for implementation cost and an observability measure as optimization objectives.

An expedited approval and implementation process based on surrogate and/or retrospective evidence may carry the risk of introducing expensive, useless or even harmful tests [ 27].

In the present implementation, an artificial neural network surrogate model is employed but the method can, in principle, be applied with any surrogate model form.

In addition, the implementation of novel image-based surrogate markers is a major task within the multidisciplinary concept of tumour diagnosis and follow-up of dedicated therapies.

These null results may have occurred because the variables used to describe the organizational domains of the conceptual model were only surrogate measures of implementation of automated eGFR reporting (Table 1).

14 Although there is evidence that well-founded and well-planned change is still a reasonable surrogate for successful implementation, 34 it was not possible in this study to track whether GPs' SMART personal objectives were carried through.

For example, there is evidence that well-founded and well-planned change is still a reasonable surrogate for successful implementation, [ 20] but it was not possible in this study to track whether students' SMART personal objectives were carried through into future undergraduate attachments or into practice [ 12].