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Described herein are vanguard and main trial recruitment activities, including strategy implementation, screening procedures, randomization results, problems encountered, and lessons learned.
We benchmarked our method and the Spark-VS implementation, screening HIV-1 protease receptor against the whole SureChEMBL library [23] downloaded in ready-to-dock format from ZINC.
Five years after project implementation, screening attendance was evaluated and it was found that only 4% of the target population had been screened.
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To facilitate implementation and improve clinician efficiency as identified in the focus groups, we developed a workflow procedure for the implementation of screening.
The implementation of screening for rheumatic heart disease at a population-scale would require a considerable increase in human resources.
We are currently funding investigations to ensure that the real-world implementation of screening mirrors the success seen in the landmark National Lung Screening Trial, where lung cancer deaths were reduced by 20percentt.
The last prescreening year was usually the year before formal implementation of screening.
This inference has serious implications for the implementation of screening methods and effective infection control strategies.
A (small) decline in metastatic breast cancer occurred around three years after implementation of screening.
Also the implementation of screening through smear tests is complex and requires routine availability of laboratory facilities.
The past three decades have seen a dramatic increase in the implementation of screening programmes for cancer in industrialised countries.
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