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This study evaluates characteristics of ciprofloxacin use prior to and following implementation of this conversion service.
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ODM items are represented as CDA assessment sections in the current implementation of the conversion tool.
Initially, it was anticipated that implementation of the conversion service would reduce the IV PO ratio, however, there were numerous variables that may have affected this endpoint.
Following implementation of the conversion service, 12% (65/554) of ciprofloxacin doses deemed inappropriate and preventable by pharmacists were still administered.
The retrospective, pre/post, unblinded design precludes the formulation of any direct causal relationships between the implementation of the conversion service and the subsequent reduction in inappropriate ciprofloxacin IV doses.
With an effective IV-PO Step-down Program in place, it is possible that the magnitude of change associated with the implementation of the conversion service may have been blunted.
In this paper, we report the successful implementation of this strategy through conversion of fused β-lactams of general structure 9 in three or four steps to keto-bridged bicyclic lactams 11.
The final fourth group of two papers is dedicated to the implementation of energy conversion technologies.
These challenges include the implementation of different conversion technologies and feedstock types, investigating the production of a superset of fuels and chemicals, systematically addressing price uncertainties for robust refinery designs, and synthesizing a supply network optimization to potentially displace the petroleum demand.
Certainly more research is required prior to implementation of crop conversion strategies as risk reduction measures.
Challenges on the road to becoming more flexible do not only occur from the technical options and limitations but also from the elements of the supply chain, including sustainable feedstock provision, the implementation of flexible conversion concepts, and the demand from the renewable energy market.
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