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766 proteins were identified by at least 2 unique high-quality peptides (>90% peptide probability) with a protein identification probability >99.9%, on the basis of Scaffold's implementation of the empirical Bayesian algorithms, Peptide Prophet and Protein Prophet, respectively [17].
The statistical test used was Wright and Simon's implementation of the Empirical Bayes method [ 89].
The LimmaGUI software, which is an implementation of the Empirical Bayes linear modelling approach, was used for subsequent statistical analysis of the resulting data [ 24].
Differentially expressed genes between these samples were found using limma (Linear Models for Microarray Analysis) package - an implementation of the empirical Bayes linear modelling approach [ 32].
The core of LIMMA is an implementation of the empirical Bayes linear modeling approach, and provides more stable inferences about differential expression.
The number of principal components to be integrated in the linear model was determined using the R package paran [ 25], which is an implementation of the empirical method of Horn's parallel analysis.
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As prior studies found cost-effectiveness results to be highly sensitive to medication adherence assumptions, a realistic implementation of the respective empirical evidence seems particularly important in health economic modeling of osteoporotic fractures [ 87].
Observations of the dependency of the effective photon path length on the optical parameters of the tissue allowed implementation of an empirical model.
Therefore, the implementation of an empirical threshold to determine significance was not theoretically valid [ 33, 34].
The empirical implementation of the model draws upon the substantial amount of technical information available.
For the empirical implementation of the model, we use the Supply and the Use matrices in monetary units for the Moroccan economy with data for the year 2002, issued by the High Commission for Planning of Morocco (2009).
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