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Further details in table 2. The gentamicin calculator page on the hospital intranet was visited 333 times during the 2-month period following implementation of the calculator.
The use of 1000 mg loading doses was significantly reduced from 52.3% (81/155) before to 27.5% (39/142) after implementation of the calculator (p<0.001).
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Following implementation of the calculators, doses were assessed prospectively.
Binary logistic regression was used to assess the significance of the difference between the number of correct doses, overdoses and underdoses, before and after implementation of the calculators.
Random samples of gentamicin and vancomycin initial doses administered during the 8 months before implementation of the calculators were assessed retrospectively against hospital guidelines.
However, the significant improvements in dose accuracy after implementation of the calculators provide an indication that they contributed to this improvement, especially as no other proactive initiatives to improve gentamicin and vancomycin dosing took place during the same period.
Prescriptions for gentamicin initial dose and vancomycin initiation regimen (loading dose and first maintenance dose) written during the 8-month period (1 January 2011 31 August 2011) before implementation of the dose calculators were retrospectively assessed for appropriateness.
This paper introduces the concepts, methods and the implementation of a calculator for the energetic long term analysis of residential settlement structures (ELAS).
The theoretical background and implementation of "Miedema Calculator", a thermodynamic platform for predicting formation enthalpies of various alloys within framework of Miedema's theory, is summarized and presented.
Figure 3 shows a clinical example of the implementation of the equation as a web calculator.
Figure 6 shows a clinical example of the implementation of the equations using the web calculator (qdiabetes.org/amputation-blindness/index.php).
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