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Laboratories place priority in the implementation of such protocols but, less than often, such protocols are not followed by the forensic scientist which is unethical.
Because the quality of service interactions can increase pricing power or market share, the implementation of such protocols is a waste of time and resources.
Consequently, some of the projects have developed such protocols themselves; yet, some of the respondents also report challenges with the development, dissemination and/or implementation of such protocols.
Michael Holsapple, executive director of the Health and Environmental Sciences Institute at the International Life Sciences Institute in Washington, DC, says that what is really needed is development and implementation of DIT testing protocols, including studies to determine "triggers" that would prompt the implementation of such protocols.
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In either case, the protocols are complex, and many optimized implementations of such protocols need verification that indeed they work correctly with respect to the specification of the system.
Although the effectiveness of PCT-guided antibiotic therapy has been proven in several randomised clinical trials, so far less is known about implementation and effects of such protocols under out-of-study conditions.
However, little is known about transfer of such protocols into clinical practice and development of antibiotic use after implementation of a PCT-guided algorithm.
Most of the works related to the validation of such protocols are based on simulation and emulation analysis of simulated/emulated implementations without taking into account formal specifications.
However, the implementation of such complex protocols requires much programming efforts and the few existing tools and libraries deal with special case protocols.
We also aimed to determine if implementation of such a protocol would lead to a reduction in the postoperative warfarin recommencement time and overall length of stay in hospital.
Also, several studies on implementation of such a protocol, partially in combination with other recommendations, have been published over the last years [ 9- 11].
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