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These results suggest that increased wild-type UCMK expression does not provide a significant enhancement in dFdC-mediated cytotoxicity and may warrant the implementation of studies aimed at engineering UCMK variants with improved activity toward gemcitabine monophosphate.
Many habitat studies have concentrated on stream features measured at local reach scales (50 150 m) and understanding the scale of potential land management impacts on SAA populations at a landscape level will require implementation of studies at larger spatial and longer temporal scales.
There is nevertheless still scope to improve the study design, the implementation of studies and their analysis and reporting in conflict settings.
We have participated in the design and implementation of studies using both probability and nonprobability sampling that have added invaluable information on various population exposures.
Together, this information should be of broad utility in the design and implementation of studies in a wide variety of human disease models.
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JKT participated in conception, design and implementation of the study.
Here we describe details of the implementation of Study-II concepts and discuss their efficacy.
Cross validation studies are essential prior to implementation of study testing to ensure that all sample processing and analytical procedures are conducted appropriately.
Coordination and implementation of study: SR, DAF, HMcL, JR.
SM, JB, MB participated in the design of the study and implementation of study protocol.
JC conceived of the study, oversaw the design and implementation of study, and drafted the manuscript.
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