The evidence from controlled trials and the implementation of stage-and disease activity-adapted regimens have particularly contributed to the improved outcome.
Comparisons with historical controls showed a benefit of the use of IVIg, but this comparison came in the context of implementation of stage-based management that included more than IVIg alone (46, 47 ).
IG, JK and WB were responsible for the clinical implementation of staging before treatment with CT, data acquisition and critical review of the manuscript.
JA was responsible for the clinical implementation of staging with the abdominal CT at the radiology department, designing the actual scanning protocol, and he functioned as consultant on findings and (additional) imaging techniques.
The design and implementation of each stage was informed by user evaluations of the previous stage.
Currently, the implementation of this stage is subject to recent research.
A class-AB implementation of output stage is advantageous in order to achieve high current driving capability with very low quiescent power consumption.
It was seen to prompt implementation of each stage of the G-AP framework and to enhance interdisciplinary working (for example, setting goals in the context of those already set or suggesting action plans under goals set by other professionals).
The institutionalisation phase entails the integration of audit into existing practice so that it becomes routine, including regular discussion of findings at perinatal review meetings and the implementation of recommendations (stage 5).
The implementation of multi-stage system with single constant power input is demonstrated to be limited only to the three-stage system where the declined pumping performance is exhibited in a four-stage system.
