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The implementation of recombination and mutation necessarily depends on the underlying genotypic representation.
The implementation of recombination is shown in Figure A3.
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To that end, we considered a deterministic, population dynamic model of HIV infection with a stochastic implementation of mutation and recombination [33] [35], and examined the viral-immune dynamics with and without recombination (see Methods).
Therefore, we would welcome the implementation of sex-specific recombination in the analysis parameters of JOINMAP.
The high efficacy of sg(B I) provided us with design principles for further implementation of nicking-directed recombination systems.
This review describes the existing strategies for SMG removal, including the implementation of site specific recombination systems, TALENs and ZFNs.
This coalescent-based composite likelihood approximation method can efficiently handle large amounts of data (Auton and McVean 2007), allows direct implementation of fine-scale recombination rate estimates and hotspot detection (McVean et al. 2004; Myers et al. 2005; Winckler et al. 2005), and considers spatial autocorrelation in recombination rate estimates (Smith and Fearnhead 2005).
This aim has been facilitated by the implementation of the Cre/ loxP recombination system in mice and the characterization of powerful cell type specific promoters driving Cre-mediated gene deletion exclusively in the target cell of interest [ 130].
There is scope for future implementation of algorithms for improving the detection and annotation of recombination, segmental duplication, and inversion events involving repetitive elements.
The results from the implementation of the GARD module in detecting recombination in the datasets are presented in conjunction with the selection analysis results.
As an example we include an implementation of bootscanning, a procedure for finding recombination breakpoints in viral genomes.
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