The present study demonstrates deficiencies in the Sweat Rate Index (specifically that it recommends restrictions that are impractical or impossible to implement) that could be improved through modifications of the index or implementation of new methodologies.
The development and implementation of new methodologies and technologies are imperative to tackle this challenge.
Concerning the ICH/GCP, an "Integrated addendum" was published on 11th June 2015, with the objective to modernize the ICH E6 Guideline by supplementing with additional recommendations which will facilitate broad and consistent international implementation of new methodologies".
However, the dissemination of new methodologies, such as stochastic or Bayesian, seems to be limited despite their (recent) implementation in software applications (see below) but could also be associated with accessibility, e.g., licensing and validation.
In this Review, Vijaya Pattabiraman and Jeffrey Bode summarize recent advances made by organic chemists working on amide-bond-forming reactions, highlighting the successful implementation of new synthetic methodologies and their limitations.
The hypothesis that impulses this research is formulated to ascertain that the learning level and the satisfaction of students will be higher after the implementation of new teaching methodologies (based on constructive learning, collaborative work, and blended learning resources), than in more traditional teaching contexts.
The main result of this paper was the implementation of a new methodology to estimate the fatigue law of the material using a strain sweep test, which allowed this fatigue analysis to be carried out in nearly 10 times less testing time than that required by the procedure described in the EN 12697-24 standard.
We introduce the newly developed risk-informed Seismic Hazard Periodic Reevaluation Methodology (referred to as the SHPRM) and present how a Senior Seismic Hazard Analysis Committee (SSHAC) Level 1 probabilistic seismic hazard analysis (PSHA) was performed in an implementation of this new methodology.
In this work, the implementation of a new methodology to design and simulate an industrial scale pressure and temperature swing adsorption process at low temperature (Cryo-PTSA) is presented, in order to produce an almost pure methane stream, with a maximum of 50 ppm of CO2, maximizing the methane recovery.
The choice for students from the first batch was due to the fact that they have experienced the curricular change and the implementation of the new methodology more closely.
