Additionally, the implementation of new methodological platforms regarding production of endotoxin free PHA nanobeads using Gram-positive bacteria opened new avenues for biomedical applications.
Additionally, the implementation of new methodological platforms such as metabolic engineering and systems biology have facilitated the controlled production of natural nanoparticles produced by bacteria, including metallic deposits of Au, Ag, Cd, Zn or Fe, virus-like particles or other nanoscale protein-only entities.
The LASI could not be easily detected before the implementation of the methodological framework.
For the implementation of the methodological tools, authorization of the relevant institutional bodies - the administration board, ethics committee and ICU directors - was required.
In this article, we present the key functionalities of the toolbox, quantify their performance, and discuss the novel implementation of important methodological concepts concerning parameter identifiability, confidence intervals and statistical tests for model validation and discrimination.
The kernel contains implementations of algorithms, methodological procedures, and fundamental objects, such as networks, chemical reactions, mathematical expressions, matrices, convex polytopes, hyperplanes, linear program solvers, etc.
However, studies on this subject are few due to limited research on implementation of programmes and methodological difficulties in conducting experimental studies on human resource interventions.
Existing reports on prototyping projects merely present their methodological set-up and results, but lack description of the implementation of the methodology.
Given recent insights into the important implications that aesthetics have for health and well-being, the aim of the present study was to re-assess the validity of the preference matrix following the implementation of a series of methodological improvements.
