Alternatively, as was done in a proteomics implementation of the exclusion list strategy, one could analyze the same sample a second time wherein the original exclusion list is enhanced with the m/ z values of modified digestion products detected in the initial LC-MS/MS analysis.
These data indicate that the deleted sequences of the targeted alleles do not contain a regulatory element that is necessary for implementation of allelic exclusion.
Here we describe a different implementation of an exclusion list approach.
As implementation of an exclusion list does not compromise the data attainable by the standard DDA approach, this strategy should prove to be useful for characterizing complex mixtures of modified oligonucleotides.
In all, 108 patients were included to the study, following implementation of inclusion and exclusion criterias.
Others point out that strict implementation of the political exclusion law would turf out a lot of the more liberal members of Libya's congress, clearing the way for political organisations like the Muslim Brotherhood, which were marginalised under Gaddafi.
We set out three categories of initiatives - fair finance, equal treatment and accountability - which could turbocharge SDG implementation by overcoming barriers of exclusion.
After implementation of all inclusion and exclusion criteria, 13,810 patients remained in the final study cohort, of whom 430 patients (3.1%) were treated with Gb at a strength of 240 mg, 7,070 patients (51.2%) at a strength of 120 mg and 6,310 patients (45.7%) at strengths of less than 120 mg (i.e. 30, 40, 50, 60 or 80 mg) at the date of the index prescription (see Figure 1).
Such discrepancies can lead to implementation of harmful treatments or to exclusion of beneficial interventions.
Given the nature and persistence of care planning and implementation barriers, the exclusion of PSWs in the RAI/MDS process is a critical area for investigation.
