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A possible explanation would be administration of topical antibiotics by the referring physicians and implementation of aggressive antibiotic regimen prior to surgical debridement at our institution.
A major advance in the general management of sepsis was the implementation of aggressive resuscitation strategies, primarily inspired from the pivotal study by Rivers and colleagues, which promoted a protocol-guided hemodynamic resuscitation based on circulatory and tissue oxygenation objectives, the so-called early goal-directed therapy (EGDT) [5].
Nevertheless our evaluation, together with its sensitivity analyses, suggest that delaying implementation of aggressive treatment would reduce the overall disease burden, and significantly lower the probability of resistant outbreaks occurring.
Only implementation of aggressive infection control measures, frequently combined with mupirocin treatment, has been successful in controlling such outbreaks.
Whether implementation of aggressive medical management in patients with diabetes with advanced calcification leads to decreased mortality remains to be determined.
Use of these markers for early identification of patients at high risk for severe disease may facilitate rapid implementation of aggressive medical and surgical CDAD therapy.
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Thus far we have revealed four independent programs: the bulk collection of telephone records, the Prism program, Obama's implementation of an aggressive foreign and domestic cyber-operations policy, and false claims by NSA officials to Congress.
Federal officials, congressional staffers, advocacy groups, and think-tank researchers know that Hamilton has helped shape Trump's various travel bans, changes to refugee policies, and the implementation of an aggressive new approach to immigration enforcement.
Oral malignant melanoma (OMM) is a rare tumor of the oral cavity with very poor prognosis despite the implementation of an aggressive treatment.
He worked with the UNC Board of Governors to develop and begin implementation of an aggressive strategic plan and selected chancellors at 11 of the 17 UNC institutions.
Beyond this reduction, the implementation of more aggressive policies or an accelerated evolution of certain technologies could untap even more savings.
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