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For successful implementation an imaging biomarker has to be fast applicable, widely available and cheap.
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This article reports a step-by-step process for the implementation of an imaging order entry system with specialized menus for an orthopedic service.
Van Atta et al. [40] have shown that implementation of an imaging protocol using US as the primary modality to evaluate paediatric patients with suspected AA leads to a decrease of CT utilization because 326 of 512 patients (63 %) did not require a CT examination.
Speculatively, an implementation of imaging to select candidates with large infarcts for cell therapy in future clinical trials may contribute to achieving better results and more homogeneous response.
We quantify the performance of these two implementations by imaging a tissue mimicking phantom.
Also, with the implementation of imaging guidelines, exam volumes would decline, leading to a decrease in income and tightening the job market for radiologists which can be a threat for the specialty of radiology.
Imaging standardization within the EU/Pharma-funded QuiConCePT project should provide a platform to support and guide the future development and implementation of imaging biomarkers in multicenter response-assessment trials.
Successful implementation of imaging and treatment monitoring using radiotracers requires detailed knowledge of their pharmacokinetics and specificity.
This also clearly includes research on the development and implementation of imaging biomarkers, defined as objectively measured indicators of normal biological processes, pathological changes, or responses to a therapeutic intervention [9].
The implementation of imaging technologies has dramatically increased the efficiency of preclinical studies, enabling a powerful, non-invasive and clinically translatable way for monitoring disease progression in real time and testing new therapies.
The need for the implementation of imaging referral guidelines in clinical routine is recognized among the radiology community worldwide, and the process is most advanced in the USA and the European Union.
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