Eq. (57) implements the hypothesis that the IDCN may have activity similar to that of the DCN, thus giving negative feedback of the output of the cerebellum to the IO system.
This section describes a neural architecture implementing the hypothesis described in Sect. 2, and a system-level model to study the interactions between multiple instances of such architecture.
In the process of identifying whether the over-represented TFBSs are only the difference between CGIs in promoter and non-promoter, the ideal method may be to implement the two-step hypothesis test on promoter-U-CGIs and promoter-M-CGIs.
d of 0.2 and the multiplied term [m−m0]+ implement
SKB implemented the research hypothesis, coded the data, and drafted the manuscript.
To investigate this possibility, we reanalyzed the data by replacing the parametric distribution implementing the null hypothesis in the original UE analysis by a distribution derived from surrogates.
To implement this hypothesis, a range of time constants governing the latency of IP3 activation are assigned to PC-IN pairs in the model (Eq. 11).
In this study we implement these hypotheses in the ecosys model to simulate water table dynamics along a boreal transition zone (ecotone) in central Saskatchewan, Canada, extending from upland black spruce forest down to a poor forested fen.
In order to filter the influence of biased G+C content, we also implemented the two-step hypothesis test on the non-redundant motifs, and the p-value cutoff in the first step is also Bonferroni-adjusted (0.01).
