These rats with LHON-like symptoms can serve as a model for future investigators to design and implement reliable tests to assess the beneficial effects of therapeutic interventions for LHON disease.
Moreover, the present methodology is easy to implement, reliable, sensitive, requiring low sample and minimized desorption solvent volume, having the possibility to tune the most selective sorbent coating, according to the target compounds involved.
To be able to make evidence-based choices on which interventions to implement, reliable information is required on both costs and benefits of interventions.
We present an original, easy to implement, reliable method of non-destructive testing of the orientation of carbon nanotubes by magnetic moment measurements performed in three perpendicular directions of magnetic field.
Even if object-oriented programming has proven to be a powerful technique, a systematic design method should also be used in order to implement reliable software, in particular in the development of simulation models.
Malik predicted that companies that implement reliable mobile payment options will do particularly well in Southeast Asia, where mobile adoption is growing rapidly.
Based on the analysis, we give guidelines for implementing reliable logout and describe a polling-based solution for creating a system-wide logout mechanisms that only requires minor changes to the existing code and does not burden the identity provider excessively.
In this work, a methodology as a means to determining and implementing reliable, understandable, relevant and accessible sustainability indicators for the interaction between the environment, the economy and the society will be examined.
Defining what the desired impact is, developing and implementing reliable methods for assessing if it is occurring, and reporting results transparently to stakeholders takes considerable effort and can feel daunting to start-up enterprises and established organizations alike.
