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We are motivated to develop a mean-field approach on two counts: first, if we can demonstrate close qualitative and quantitative behaviour between the mean-field and stochastic models, then it may be far simpler to implement predictions based on analytic calculations rather than running full simulations.
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White-box and black-box techniques have been described in literature to implement prediction models.
If we're going to implement prediction algorithms, we must also make them transparent and allow people to challenge their findings (which means we need to educate everyone about them so they know what questions to ask).
Without thorough evaluation of diagnostic performance, it is unsafe to implement prediction models in clinical practice for decision support.
It explains how to implement prediction pipelines, offers more detailed information on the functionality of FRED and addresses problems like choosing the right prediction method or threshold.
pombe orthologs, suggesting that methods that implement prediction of HI based on gene properties could be crucial for identifying HI genes a priori in different species.
The WinBUGS 1.4.3 [27] and R [30] source codes for our Bayesian approach, as well as the implemented predictions and graphs, are available in Methods S1 and Methods S2 (more detailed information can be found in the website http://homepage.ntu.edu.tw/~ckhsiao/download.html).html
Finally, studies that focus on the impact of prediction models on clinical practice, ideally by trials of a clinical decision support system, are an essential final step when implementing prediction models in clinical practice.
The states of the underlying HMM and the implemented prediction algorithms determine which type of data analysis can be performed, whereas the parameter values of the HMM are chosen for a particular data set in order to optimize the corresponding prediction accuracy.
In addition, we implement PPI predictions to interpret biological data.
Mammalian and bacterial leadless secreted proteins have been collected and used to implement the prediction software, SecretomeP, for predicting these proteins (http://www.cbs.dtu.dk/services/SecretomeP/) (38, 39).
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