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The conditions needed to discover positive allosteric modulators in a HTS are reasonable and simple to implement, generally requiring consideration of the ligand concentration in a screen.
The conditions necessary for the discovery of negative allosteric modulators in a high-throughput screen are quite reasonable and simple to implement, generally requiring a consideration of the ligand concentration in a screen.
Although a systematic review of reviews on the public health role of the midwife [ 20] identified several midwifery interventions from review evidence that midwives could implement, generally, the evidence was very limited.
And some policies and practices do tend to undermine the responsiveness of health care staff to patients as persons, for example, when standardized checklist approaches are used inflexibly to help implement generally effective interventions in the pursuit of measurable aggregate reductions in disease, disability, and death (Rhodes et al. 2006).
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To get a clear picture of how this provision affected women's choices about family planning, I compared women from across the U.S. at ages affected by the provision before and after it was implemented, generally between the years 2006 and 2013, to a control group of slightly younger and slightly older women, who did not gain new eligibility.
Mostly this was in one region of the country, as the new methods were only being tested rather than implemented generally, and this was usually in a region where the study was promoting or re-promoting questionnaire return at that time.
All of this is in sharp contrast with the conventional snow shovel, a modern implement of generally poor design that has been blamed for many a wintertime back strain.
Several reasons justify the use of this classifier: it is straightforward to implement; it generally leads to good recognition performance thanks to the nonlinearity of its decision boundaries; and its complexity is assumed to be independent of the number of classes.
Using simulated data based on real data from the HapMap project, we show that PLS-based MLAS are simple to implement, and generally provides improved power in diseases genes mapping relative to tagSNPs-based MLAS, PCA-based MLAS and TSM-based MLAS.
Bonuses are easier to implement and generally do not require negotiations or rewriting existing contracts.
In conclusion, EMDR is difficult to implement and generally inappropriate for the Indonesian context, particularly given the limited basic counseling skills of child workers in conflict zones but also because of the questionable cultural appropriateness of the technique.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com