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Endometrial receptivity gene signature during the implantation window does not vary significantly among patients with endometriosis even considering different stages compared with healthy women.
To evaluate the clinical response and endometrial morphology during the implantation window on ovarian hyperstimulation with the aromatase inhibitor letrozole in infertile ovulatory women.
To compare the concentration of glycodelin in uterine flushing at the implantation window obtained from women with subseptate uteri, women with a history of recurrent first trimester miscarriage and fertile controls.
To determine whether the expression of leukemia inhibitory factor during the implantation window in endometrial tissue and uterine flushing fluid of patients with adenomyosis differs from that of healthy fertile women.
All these results suggest that CD98 might be a crucial determinant of human endometrial receptivity during the implantation window.
This period, termed the "implantation window", lasts from 4 5 days to 9 10 days after progesterone production or administration.
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Mice deficient for CD147 (also known as basigin or EMPRINN) were reported to have implantation defects [15], and CD147 expression is restricted to the peri-implantation window in rat [16]; however, in humans, endometrial expression of this molecule appears to be less restricted [17].
The peri-implantation window in pigs is characterized by the coordinated interactions between the maternal uterine endometrium and the rapidly elongating conceptuses and represents a period of time during which a large percentage of the developing conceptuses are lost.
Second, implantation of window chambers invariably induces a certain degree of inflammation that might confound the findings related to tumour angiogenesis.
The spheroids were then allowed to grow in coated culture flasks before implantation in window chambers (liquid-overlay culture technique) [ 32].
Outside of this window, implantation is unlikely to occur, probably because of changes in the receptivity of the lining of the uterus.
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