Exact(5)
These risk variants are likely to show incomplete penetrance and imperfect segregation with disease as most variants have also been observed in non-autistic controls [5], [6].
Upon imperfect segregation of plasmids after cell division, plasmidless daughter cells are destroyed by elevated toxin levels due to the rapid breakdown of the unstable antitoxin and lack of its further synthesis [158], [159].
Understanding such epistatic interactions may be crucial in explaining the imperfect segregation of mutations with mental illness in humans [ 1].
This may also reflect an imperfect segregation apparent in the functional characteristics of the cardiac vagal ganglia in individual rats where selective electrical stimulation of the ganglia was attempted (Sampaio et al., 2003).
Even well-established risk loci for autism, ID, schizophrenia and other neurodevelopmental syndromes provide examples of imperfect segregation, as shown by exonic CNVs in NRXN1, missense mutations in SHANK2, rare sequence and structural variants in CNTNAP2, microdeletions and microduplications at 16p11.2.
Similar(55)
Delocalization of Spo0J from either side of the nucleoid would indicate imperfect nucleoid segregation.
Wolbachia presence in B. malayi P3 and P4 germline precursors is due to imperfect asymmetric segregation.
This grouping was concordant with comparable 4-way cluster structure recently reported by the TCGA.[26] Integration of copy number aberration, mutation and expression of EGFR, PDGFRA and NF1 revealed that three of the transcriptomal classes were enriched for alterations in each gene, respectively, although the segregation was imperfect.
Third-order correlations are only useful for motion estimation because of light dark asymmetries in natural stimulus statistics (Fitzgerald et al., 2011; Clark et al., 2014), so this result implies that ON/OFF segregation provides an imperfect way to account for the complexity of light dark asymmetries found in the natural world.
Its two parameters are suitable for representing two se situations existing in the case of unmixed feed, namely, imperfect mixing of the feed and partial segregation of the reacting mixture.
The book, written before Barack Obama's ascent, includes a helpful note at the end on what busing and segregation were all about, evenhandedly describing busing as a imperfect solution to an intractable problem.
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Justyna Jupowicz-Kozak
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