Sentence examples for imperfect normalization from inspiring English sources
An imperfect normalization procedure can bias the or induce new sources of latent structure shared across probes (Dabney and Storey, 2007).
Imperfect normalization of glucose metabolism by replacement insulin therapy may alter the concentrations and compositions of potentially atherogenic lipoproteins [ 11, 12].
However, the larger assembly size, greater number of unigenes, and shorter unigene lengths observed in our data set relative to the ESTcalc prediction may be explained by imperfect cDNA normalization or inefficient de novo assembly.
In standard fMRI methods, the large voxel-size, along with the combined effects of partial-voluming, pooling due to shared vasculature [12], imperfect alignment during normalization and group averaging, and spatial smoothing all conspire to bias fMRI analyses towards findings of spurious overlap [13].
Furthermore, any length normalization is imperfect because so many annotated loci have multiple transcripts of different lengths.
Some regions, including δ7.00 7.25, δ7.86 8.00 and δ8.05 8.20, were discarded after the normalization because of imperfect peak alignment.
