Sentence examples for imperfect leading from inspiring English sources

Nevertheless, the fidelity of folding is imperfect, leading to off‐pathway intermolecular interactions that compete with proper folding and to consequent formation of thermodynamically stable aggregates.

10 Scleraxis expression is increased during the repair and remodelling stages of tissue healing, as the tendon attempts to restore its phenotype this attempt to restore normal tendon phenotype following injury is frequently imperfect, leading to metaplastic or fibrotic change in injured tendon.

However, existing methods are imperfect leading to incorrect calls and uncalled genotypes ("no-calls").

The problem of unnecessary patient exposure to radiation could arise from two sources: 68Ge breakthrough that is not removed in the labelling process and possibly imperfect labelling, leading to an insufficient yield and, hence, to free 68Ga in the radiopharmaceutical.

Fourth, toxin tests are imperfect, potentially leading to overestimation of incidence.

This process is made possible by the perfect pairing of miRNAs and mRNAs or their imperfect pairing leading to cleft mRNAs of protein coding genes.

Grossberg et al. demonstrated that a 90 day period of pharmacy refill was associated with VL change, [ 19] but refill periods shorter than 60 days may overcall imperfect adherence leading to unnecessary clinical interventions [ 17].

Wound healing after dermal injury is an imperfect process, inevitably leading to scar formation as the skin re-establishes its integrity.

The authors suggested that p16-dependent senescence was an artefact of imperfect culture conditions, leading to 'stress' (Ramirez et al, 2001).

The contention is that such measures are imperfect and often biased, leading to dysfunctional rationing of fundraising and administrative infrastructure.

In reality, such assumptions are usually not satisfied leading to imperfect models as is the case with the ELEA dataset [38].