Sentence examples for impeding function from inspiring English sources

A common consequence of AGE accumulation is covalent cross-linking of AGEs to proteins, which leads to increased stiffness of protein matrix, impeding function and increasing resistance to removal of cross-linked proteins by proteolysis in various tissues and organs leading to impaired organ functions (Singh et al. 2001).

However, in this instance the cost of additional genetic testing may have an impeding role.

Due to prolonged neglect a number of these were of impressive proportions, e.g. an 18 x 12 cm lipoma, which was impeding normal daily function and impairing quality of life.

Our experiments reveal a crucial role of TStrC derived from paediatric cancers in impeding immune cell functions.

In this context, to be able to promote Sirt1 expression at the right moment appears to be crucial to improve motor function without impeding muscle formation.

Thus, calreticulin deficiency alters nuclear pore function and structure, impeding myofibrillogenesis in nascent cardiomyocytes through a calcium dependent mechanism.

Once the transcriptional activator has vanished, expression of the gene of interest is lost, impeding genetic fate mapping in zebrafish.

Biosynthesis of oligosaccharides is difficult to control and typically results in heterogeneous structures, impeding efforts to elucidate the biological functions of these molecules.

The same dynamic could be impeding adults' efforts to use exercise to trim away flab.

Accordingly, impeding gate opening by crosslinking or mutagenesis impairs PCC function (Trueman et al., 2012; du Plessis et al., 2009).

The K. pneumoniae capsule has previously been implicated in impeding adherence to cells by physically shielding short adhesins, negating their function [31], [32].