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The need to assemble and integrate data across studies during ancillary study workflows can pose a key impediment to using a CTMS alone for ancillary study management.
This method was recently extended to incorporate SNP (single nucleotide polymorphisms) by replacing A by a genomic relationship matrix G[ 14], although there is no impediment to using A and G together [ 15].
Moreover, methods have been developed to incorporate both individual patient data with summary level data when necessary, so that having partial IPD should not be an impediment to using a one-stage approach [ 5, 11].
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Know that this may be the biggest impediment to using an active tactical asset allocation approach, because once you get past all the hurdles listed in this article, then you have to pull the trigger and make the trades, no matter what your so-called better judgment is telling you.
"The idea that the failure to give Miranda warnings is a great impediment to using federal courts is a simplistic falsehood," Rona said.
This capacity loss is now a key impediment to using lithium-ion batteries in hybrid vehicles, which could be exposed to these conditions.
The inability to evaluate for deterioration in early generations is a common impediment to using these disease-resistant accessions as parents in breeding.
Two participants noted that the frequent changes in consent form language could be a significant impediment to using the grid for as yet undefined research and that it was therefore critical to deal with the consent issue as a community.
"High patient load" is the first barrier to the desired mutual understanding because all participants agreed that this is an important impediment to using the ideal communication style.
"What I have heard a lot is that the cost of getting licensed, purchasing, insuring, maintaining and fueling a car has become an impediment to use of a car.
This is likely to act as an impediment to use of these measures in clinical settings.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com