Sentence examples for impedes the binding from inspiring English sources

-Zuonin A also binds JNK but barely impedes the binding of c-Jun.

The authors of the previous reports proposed that steric hindrance is one of major factors that impedes the binding of 5-substituted C in the hAID catalytic pocket39.

The natural inhibitor of the IAPs is the protein Smac, which impedes the binding to the caspases.

Secondly, due to the large molecular dimension of carrier proteins, a shielding or masking effect may occur that impedes the binding of pAbs to the conjugated haptens [ 17].

Our data strongly suggest that: i) Cys PEGylation does not hamper the binding of the αN Ab to the caleosin but impedes the binding of the FL Ab, and ii) the FL Ab only recognizes the C-terminal part of the protein.

If true, then it could be predicted that self-compatible S-pollen protein should bind the active pocket region, thus impeding the binding of the general inhibitor.

Soluble VEGFR2 fragments can bind endogenous VEGF, thereby blocking the action of VEGF and impeding the binding of VEGFR1, VEGFR2, and VEGFR3 to cell membrane ligands, inhibiting the VEGF-induced signaling pathway, and preventing angiogenesis [ 8].

Epigenetic marks can cooperatively regulate chromatin accessibility and in turn facilitate or impede the binding of regulatory factors to various elements, suggesting their important roles in regulatory circuits.

This is usually due to point mutations in the BCR-ABL ATP-binding site, that impede the binding of imatinib [11].

PEGylation impeded the binding of the FL Ab to the protein, leading to the loss of fluorescence.

H3R2me2 has been found to impede the binding of effector proteins to H3K4me3 and thus to control gene expression [ 28].