Sentence examples for impeded the binding from inspiring English sources

PEGylation impeded the binding of the FL Ab to the protein, leading to the loss of fluorescence.

Whereas in our study, the use of cells expressing receptors containing site-specific point mutations impeded the binding of endogenous skelemin but not the interactions of other cellular proteins with the integrin tails.

-Zuonin A also binds JNK but barely impedes the binding of c-Jun.

If true, then it could be predicted that self-compatible S-pollen protein should bind the active pocket region, thus impeding the binding of the general inhibitor.

Soluble VEGFR2 fragments can bind endogenous VEGF, thereby blocking the action of VEGF and impeding the binding of VEGFR1, VEGFR2, and VEGFR3 to cell membrane ligands, inhibiting the VEGF-induced signaling pathway, and preventing angiogenesis [ 8].

The natural inhibitor of the IAPs is the protein Smac, which impedes the binding to the caspases.

The authors of the previous reports proposed that steric hindrance is one of major factors that impedes the binding of 5-substituted C in the hAID catalytic pocket39.

Epigenetic marks can cooperatively regulate chromatin accessibility and in turn facilitate or impede the binding of regulatory factors to various elements, suggesting their important roles in regulatory circuits.

This is usually due to point mutations in the BCR-ABL ATP-binding site, that impede the binding of imatinib [11].

H3R2me2 has been found to impede the binding of effector proteins to H3K4me3 and thus to control gene expression [ 28].

It should be noted that under this model, amino acid sites involved in specificity determination are the ones impeding the binding of the self-compatible pollen protein.