Sentence examples for impeded sequence from inspiring English sources

A high GA content and repetitive nature of this locus impeded sequence analysis, as polymerase slippage resulted in low-quality sequence results.

As nemaline myopathy (NM) is genetically heterogeneous and as the immense size of the nebulin gene significantly impedes classical sequences approaches [ 12], we performed exome sequencing on 5 μg of genomic DNA from the patients and their parents as in Böhm et al. [ 15].

Although the predicted S. gregaria precursor displays putative hallmarks of an NPLP precursor, comparative sequence analyses of NPLP precursors have revealed substantial heterogeneity among different species, impeding unambiguous sequence-based identification of NPLP orthologs.

Unbiased sequencing not only poses an enormous data processing burden, but also impedes deep sequencing.

This low level of conservation in amino acid sequences impeded a reliable survey of the complete superfamily (Adams et al. 2000).

Because SRs are strongly associated with their AR, the advantage of PS method lies in its local assembly which is less impeded by repetitive sequences.

However, the use of these pol III-dependent promoters limits the design of antisense RNA, because pol III transcription was found to be impeded by several sequences, which prematurely terminated the transcription (He et al, 1997; Das et al, 1988).

Most likely they overlap with the highly heterochromatic tomato centromeres (Chang et al. 2008) containing repetitive sequences which impeded the de novo assembly of the reference sequence.

Nonetheless, the complexity of proteins, the subtlety of the determinants of folding, and the exponentially large number of possible sequences impede the search for peptide sequences compatible with a desired structure and function.

The inability to predict long noncoding RNAs from genomic sequence has impeded the use of comparative genomics for studying their biology.

This arrangement has impeded efforts to fully sequence the genome of Eimeria, which remains the last of the major apicomplexans to be fully analyzed.