Data also indicate that tourniquet assistance during TKA impedes progression in an objective-based measure of physical performance, such as muscle strength and knee range of motion [9].
In vitro results imply that miR-145 is suppressive, and impedes progression of urothelial carcinoma cells.
Decrease of NF-κB activity impedes progression of degenerative phenotype in mice with knocked out Sirt6 window sirtuin gene [ 15].
Three-step radioimmunotherapy promises to have an important role as adjuvant treatment in high grade gliomas, particularly in glioblastoma where it impedes progression, prolonging time to relapse and overall survival.
COUP-TFII activates PPAR γ expression and simultaneously inhibits Runx2 activity, thus promoting the entry of mesenchymal progenitors to the adipocyte lineage, while impeding progression to alternative lineage pathways.
This results in a reduced dwell time of SERT in the conducting state, because high internal substrate concentrations favour re-association of substrate to the internal substrate-binding site and thus impede progression through the transport cycle.
Studies showing the nucleus-limited nature of DNA damage checkpoint signal in S. cerevisiae (Demeter et al. 2000) are germane to the second model because they demonstrated that of two nuclei sharing the same cytoplasm, the one with damaged DNA arrests in mitosis without impeding progression through mitosis of the other with undamaged DNA.
The dispersed-particle interlayers delayed the onset of interlaminar delamination from the free edge and impeded the progression of interlaminar delamination until final failure.
Even then, viral infection and shRNA expression was limited to a small area around the injection site, resulting in spatially limited suppression of PrPC expression, modestly impeded disease progression and unaltered disease incidence.
