Sentence examples for impede sustained from inspiring English sources

While these mutations all severely disrupt endophilin-A BAR tubulation activity in reduced systems, neither of them prevented development of the fly rescuants to adulthood, nor did they significantly impede sustained synaptic activity at the larval NMJ.

Otherwise, the presence of tumor cells without the targeted defect will guarantee tumor growth and impede sustained response to therapy.

These concerns can constrain initiation of treatment for all women with indicated need, or may impede sustaining therapy over the recommended timeline established for the particular regimen, once treatment has been initiated [ 15, 16].

Indeed, Mr. Geither and Mr. Summers soft-pedaled the possibility that taxes would have to be raised to close a more than $1 trillion deficit that they said would impede a sustained recovery, but they refused to rule out such tax increases, even on the middle class.

While outbreaks of different strands of Ebola occur every few years, the virus's delicate composition has impeded a sustained attack.

There were no fiefs or demesnes or benefices or escheats to impede the largest sustained landgrab in the history of the world.

Thus, the format of the Understanding Dementia MOOC appeared to invite students from a variety of educational backgrounds and to facilitate, rather than impede, their participation and sustained engagement in learning.

But the old habits remain, with the Republicans at the forefront of impeding a concrete and sustained climate change plan.

Other factors that may result in sustained venous hypertension are those that impede the pumping function of the leg muscles, such as conditions that reduce spontaneous movements (Parkinson's disease, stroke, spinal cord injuries or excessive sedation).

Actually, phosphorylation of SOCS1 triggered by the oncogenic v-Abl kinase impedes the SOCS1-Elongin B/C interaction, leading to sustained JAK/STAT signaling [ 69]. v-Abl signaling induces multiple serine/threonine kinases including members of the Pim kinase family.

All these studies suggest that USP18 disruption can impede its negative regulatory effect on IFN signaling, resulting in sustained JAK STAT activity and antiviral activity.