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A DGEN is subject to evolutionary perturbations (e.g., gene deletions, rewiring, duplication) that may be lethal, or that may impede development, for the corresponding organism.
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"We have impeded development for more than six months; many families have been rehoused in better situations, and we have shone a bright light on the vile processes through which poor and working people are being cleansed from the capital".
ClinicalTrials.gov NCT00594373 The lack of biomarkers of efficacy and safety continues to impede development of microbicides for the prevention of HIV.
However, this should not impede development of additional HR mutants for vaccines.
Caps must not impede development of broadband.
The human brain is complex and difficult to study, which has impeded development of drug treatments for mental illnesses.
Senators Dorgan and Voinovich introduced a bill that would address many of the issues that have impeded development of transmission lines needed for renewable energy.
Glickman also briefly mentions arguments that segregated schools were undemocratic because they impeded development of the "capacities" of citizens for political participation.
More importantly, for each isolate, microsporidian infection enhanced the melanisation response (and perhaps other immune responses) and impeded development of malaria, which suggests immune-priming as a mechanism.
Little is known about the host factors required for the replication cycles of these viruses in either of their host genera, which impedes development of antiviral treatments.
These gaps have impeded development of control strategies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com