In apoptotic cells, AMN seemed to work as a physical barrier impeding active caspases to reach the cellular cortex and plasma membrane.
In the present study, we show new data demonstrating that AMN indeed works as physical barrier impeding active caspases to reach and cleave critical proteins in the cellular cortex and plasma membrane proteins to preserve plasma membrane integrity.
Lorna is on regular dialysis, but that doesn't impede her active social life or babysitting her grandchildren.
It is our view that contracts with the public sector should not, other than in exceptional circumstances, impede the active release of information by providers, and published information should be accessible and as easy as possible to understand.
The considerable reduction in TET expression observed at the Teff stage should impede any active demethylation through the oxidation of either 5mC or 5hmC (a process that involves TET activity), thereby averting long-term PD-1 expression that would affect Teff function.
Specfically, we wanted to know if inactive β2ARs could impede internalization of active β2ARs, or alternatively if active β2ARs could promote internalization of inactive β2ARs [8], [10] [11], [11].
Lack of coassociation between PRCs and S2p thus supports an "on-off" (digital) switch mechanism of PRC regulation, where PRC impedes establishment of active RNAPII at PRC-bound chromatin.
In essence the electrode may impede substrate access to the active site of the enzyme.
Once the person producing the music (or video, which is thousands of times more complex) takes active steps to impede automated identification, you're talking about the kind of computer science problem that hasn't even shown promising research approaches yet -- let alone actual, field-ready, tested technology.
Embedding the phosphine ligands within a cross-linked structure did not strongly impede mass transfer toward the active centers, as proved by fast metal coordination and a catalytic activity tantamount to that of higher chain mobility micelles or core-cross-linked micelles that have phosphine moieties located on flexible linear arms.
