Sentence examples for imparting signals from inspiring English sources
Other collagens such as types III, V, and VII are also altered in expression and deposition in breast cancer [ 64, 103- 105], undoubtedly imparting signals that lead to loss of structure and function in the breast.
This is surprising in light of (a) the complex and still little understood transcriptional programs that drive fate determination in memory T cells, and (b) the fact that IL-15 and IL-2 impart signals to antigen-activated T cells through the common IL-2/IL-15 receptor βγ chain.
These molecules provide the appropriate adhesion to enable traction and movement of the cells and/or impart signal between the ECM and the cell interior.
Understanding how ECM imparts morphoregulatory signals to breast epithelium is of importance also in carcinogenesis.
Thus, poorly degradable type I collagen imparted senescence signals on both replicating and nonreplicating but stressed SMCs.
CD25 may impart environmental signals, whereas high plasma levels of enzymatically cleaved, soluble CD25 in AML may suppress the antitumor response via competition with the lymphocyte surface CD25 for IL-2 and have long been shown to be associated both with the burden and severity of the disease.
The current study concludes that downregulation of NEP in prostate cancer epithelial cells allows mitogenic peptides to impart growth signals to the developing tumour, while in the surrounding prostate stroma elevated ECE-1 provides a local source of active ET-1 which encourages invasion.
A Bluetooth device detected via Bluetooth discovery imparts a signal strength which can roughly indicate the distance between the two devices [19].
By comparing a CRAC channel mutant that is active in the absence of STIM1 and hence does not aggregate at ER-PM junctions with channels that re-localize to these sites, we have examined whether CRAC channel proximity imparts a signaling advantage to excitation-transcription coupling.
In addition to imparting specific bioactive signaling, our crosslinking studies show that the mechanical properties increase proportionally when 0.5% and 1.0% concentrations of the OGP crosslinker are added.
In this work, we describe improving the direct SMRT sequencing of 5mC via mTet1-mediated oxidation to 5caC, thereby reducing the relatively high sequencing coverage required to detect the subtle signals imparted by 5mC with high confidence.
