Exact(2)
These studies suggest that CD44 plays an important role in HNSCC tumor initiation by imparting cells with enhanced anoikis-resistance properties and/or stemness.
This decomposition pathway could potentially lead to novel resistance mechanisms whereby intracellular levels of Pi/active Pi esters or other catalytically active Brønsted-Lowry bases are elevated in concentration, imparting cells with modest resistance to 90CE and its prodrugs.
Similar(58)
Here, both genetic and chemical strategies were used to impart cell-specific targeting to the Hsp cage from Methanococcus jannaschii.
We successfully imparted cell-resistant properties to gold and platinum surfaces using gold- and platinum-binding peptides, respectively, in conjunction with PEG.
This approach for the rapid creation of highly-cellularized constructs with soft tissue like mechanics offers an attractive methodology to impart cell-derived bioactivity into scaffolds providing mechanical support during the healing process and might find application in a variety of settings.
RNA splicing is an important event that significantly increases proteomic diversity and may impart cell specificity.
However, whether short synthetic peptides containing LKMTADFILQ amino acid sequence alone can selectively bind to the bacteria with similar specificity or the 10-amino acid sequence imparts cell wall binding capability only in the context of larger PlyG protein is not known.
Additionally, aberrant EGFR signalling imparts SCCHN cells with classic tumour cell characteristics, including decreased apoptosis, enhanced invasiveness, migration, angiogenesis and metastasis.
ERG expression alone in PC-3 cells imparted upon these cells a more invasive phenotype.
Epigenetic modifications are an important aspect of biology, as they impart to cells the capacity for cellular plasticity and may also act, in response to intrauterine triggers, to program cells in preparation for the extrauterine environment, essentially priming the genome of the developing fetus for the world outside the womb.
It also could impart those cells the ability to form the tumor in vivo.
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