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Depletion of the cancer stem cell population greatly impairs the potential to initiate xenograft tumor formation of the bulk tumors [1], [2].
Thus, it can be assumed that this high unspecific background concentration of MMP-9 in serum probably impairs the potential diagnostic/prognostic performance of this parameter.
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They may also impair the potential applications in Vehicular Ad hoc Networks (VANETs) by creating an illusion of traffic congestion.
Lack of surrounding adult canopies did not seem to impair the potential recovery of the system, suggesting that in these systems recovery could be actively enhanced even following severe depletions.
Lack of surrounding adult canopies did not seem to impair the potential for assisted recovery, suggesting that in these systems recovery could be actively enhanced even following severe depletions.
Despite this the conflict with time may greatly impair the potential influence of this tool.
These data demonstrate that MegaFasL reduced tumor burden within animals to undetectable levels by PCR assay, and significantly delays the development of paresis at concentrations that do not impair the potential of HPC to engraft, persist and differentiate in vivo into the expected hematopoietic lineages.
IgM memory B cells have been shown to be important in providing early defence against pneumococcal infection, and the loss of IgM-producing B cells has been shown to impair the potential to generate adaptive immune responses (Boes et al., 1998; Kruetzmann et al., 2003).
In east Asia and the Pacific, where the population is ageing, labour income losses represent 0.25% of GDP, while in sub-Saharan Africa, where air pollution impairs the earning potential of younger populations, such losses represent the equivalent of 0.61% of GDP.
MiR-199b-5p over-expression blocks expression of several cancer stem-cell genes, impairs the engrafting potential of MB cells in the cerebellum of athymic/nude mice, and of particular interest, decreases the MB stem-cell-like (CD133+) subpopulation of cells.
Our findings are also consistent with a previous report that riluzole, which blocks persistent Na+- and Ca2+-currents [33] and thus impairs the action potential propagation, attenuates ET-induced glutamate release in the mouse hippocampus [20].
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