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Disruption of iron homeostasis always impairs the functions of these iron-requiring proteins and is genetically associated with diseases characterized by DNA repair defects in mammals.
We showed that knocking down Cav1.2 and/or Cav1.3 subunits impairs the functions of Th2 lymphocytes and is beneficial in experimental models of asthma, while it has no effect on Th1 cell functions.
Studies over the last 30 years have clearly demonstrated that chronic ethanol abuse impairs the functions of both T cells and B cells.
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The mucus also impairs the function of the cilia, the fine hairlike projections on cells that are crucial to cleaning the airways.
Simple steps to improve your digestive capacity include chewing food thoroughly, drinking as little as possible at meal time (drinking impairs the function of acid and/or digestive enzymes) and avoiding meals late in the day.
The direct effects of brain tumours are replacement or compression of tissue, which impairs the function of the compressed part and often causes epileptic seizures.
Uremia can result from any disorder that impairs the functioning of the kidneys or that hinders the excretion of urine from the body.
The onset of cardiac fibrosis post myocardial infarction greatly impairs the function of heart.
SARS M protein is associated with TRAF3, which is crucial for the IFN responses and impairs the function of TRAF3-TBK1-IKKε (Siu et al., 2009).
Not only does the debt cast a dark shadow over the lives of millions of young Americans, it impairs the functioning of the economy.
It has been reported previously that phoshorylation of Ser16 of Pin1 impairs the function of Pin1 [12].
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