In this context, an increase in the information asymmetry can impair the access to bank debt (De Andrés Alonso et al. 2005; García-Teruel et al. 2014b) and create bank credit rationing (Stiglitz and Weiss 1981).
A balanced approach between innovation and cost-effectiveness must be sought to provide patient acceptability without impairing the access to patients of new medicinal products.
The result obtained with tetrasulfonated conjugate 40 might be due to the bulkiness of the dendrimeric part of the molecule, which might impair the access to the MET peptide and/or to the Gly-Tyr dipeptide unit.
It is possible, for example, that rumination impairs the ability to access lifetime period knowledge, limited working memory capacity impedes access to general event information and that functional avoidance of negative affect might limit access to event specific knowledge.
This kind of instrument is adequate to evaluate medicines prescribed for high-prevalent acute conditions, but impairs the evaluation of medicine access for chronic diseases, since under this circumstance the visit to the doctor may have happened long before the adopted recall period [ 9] and does not detect the access to medicines that are not dependant on prescription.
The low sensitivity of the galactomannan determination in serum samples from non-neutropenic patients may be a consequence of two factors: the clearance of GM by circulating neutrophils and the less angioinvasive forms of Aspergillus infection in these patients that impair the access of GM to the blood stream [ 18- 20].
The presence of proximal vasospasm impairing the arterial flow in the access artery can alter the hemodynamic pattern of the arterial feeders in the target area, thus rendering embolisation impossible.
If a lower arthroscopic infusion pressure of 40 mm Hg does not impair the surgeons view and access, we recommend its use to reduce the risk of patients developing severe postoperative pain.
We work as you know on accessibility for the visually impaired, access in the developing world through Research4Life, and are against government-imposed sanctions on who can read what in certain countries around the world.
Sphingosine-1-phosphate was demonstrated to have a key role in vascular permeability (Garcia et al, 2001) and recently low levels of circulating S1P were linked with progression of leaky vessels (Camerer et al, 2009), a known phenomenon in tumour biology that impairs chemotherapy access to tumour cells.
